Name | suxamethonium chloride |
Synonyms | midarine Anectine suxamethonium chloride Succinylcholine chloride Succinylcholine Chloride Choline,chloride succinate Succinylcholine Chloride (500 mg) succinylcholine chloride (anhydrous) 2-dimethylaminoethylsuccinatedimethochloride (2-hydroxyethyl)trimethylammoniumchloridesuccinate 2,2-succinyldioxybis(ethyltrimethylammonium) dichloride 2,2'-(succinylbis(oxy))bis(N,N,N-triMethylethanaMiniuM) chloride 2,2'-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[n,n,n-trimethyl-ethanaminiudi |
CAS | 71-27-2 |
EINECS | 200-747-4 |
InChI | InChI=1/C14H30N2O4.2Cr/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;/h7-12H2,1-6H3;;/q-2; |
Molecular Formula | C14H30Cl2N2O4 |
Molar Mass | 361.3 |
Melting Point | 164 °C |
Merck | 8875 |
Storage Condition | Refrigerator |
Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
Physical and Chemical Properties | White or almost white crystalline powder, odorless and salty. Melting point 156~163 ℃. It is easily soluble in water, the aqueous solution is acidic, the chemical properties are unstable, and it is easy to decompose. It must be stored in a refrigerator. The drug used clinically is succinylcholine chloride. Laboratory preparation of succinylcholine chloride method: It is prepared by the condensation reaction of succinyl chloride and choline chloride. This product is a striated muscle relaxant, commonly used as an auxiliary drug for general anesthesia, its characteristics are fast effect, short duration, so easy to control. The disadvantage is that large doses can easily cause respiratory paralysis. Structural formula of succinylcholine chloride dihydrate |
UN IDs | 3249 |
RTECS | GA2360000 |
Hazard Class | 6.1(b) |
Packing Group | III |
Toxicity | LD50 i.v. in mice: 0.45 mg/kg (Anttila, Ertama) |